Don't have problems with Command & Conquer: Generals & VISTA
Have 2 PC's with Windows Vista Premium Home and can play on both, one even a simple laptop PC...
What version of C&C Generals...?
What version of C&C Generals Zero Hour...?
I play on v1.08 (Generals) and v1.04 (Zero Hour)
I also use a NO-CD crack and can paly always even if I don't have my Disc's with me...