If you do a search for the first sentence of that you can find stuff all over the web with nearly identical setups
I'd grab a trial copy of avg antivirus/antispyware. Well to be honest, I'd trash McAfee and buy the version of avg for $35. Much better protection. The only thing it's missing is the firewall but I'd think you're better off with a free firewall over McAfee's anyways. From my experience their software is junk!
Big question is, do you have a router? If she's aware of what she's doing on the web and you have a router, I may not even worry so much about a firewall...
-Kevin
BruceV - Post up scans using hijack this. I wouldn't trust just one anti-malware program if there's evidence of an infection. No av program is perfect! On a side note, you'd probably be better off opening your own thread for it, that way we can comment on each problem specifically rather than trying to help two people in one thread! The problems seem similar but they may be very different...