[UD] what is this

**korgul** · January 26th, 2002, 12:30 PM

I was sitting here drinking my coffee watching the molecules go by on the new protein and noticed that it said " de novo structures" what is this? Usually I see some # then conformers?

I seen this a couple times before but never paid any attention to it. Now it has got me curious.

DENOVOSTRUCTURESCONFUSEDkorgul

**surreal** · January 26th, 2002, 12:37 PM

De novo structures—Sometimes a molecule may have extra potential if it slightly altered in some way. THINK considers small variations or atom substitutions to increase the number of molecules being evaluated.
These new altered molecules are de novo derivatives, or structures, which are also tracked on the screensaver.

is she a genuis? or is it google?

genuis!

**surreal** · January 26th, 2002, 12:41 PM

Actually this is a good page of definitions.

**korgul** · January 26th, 2002, 12:47 PM

Thanks surreal.

The UD queen comes through once again.

korgul

**surreal** · January 26th, 2002, 12:56 PM

Methinks I'm too imature to be queen.

Just call me Princess

**Max_Confusion** · January 26th, 2002, 01:26 PM

So Princess... What is a VEGF protein?

Just curious...

**phenious** · January 26th, 2002, 01:49 PM

I think I will step in for this one.

Vascular Endothelial Growth Factor
Vascular Endothelial Growth Factor (VEGF) stimulates the growth of blood vessels. The uncontrolled growth of cancer cells is legendary. But this sort of growth requires a lot of blood flow to the cell area. If the blood vessel growth can be restrained, then, in theory, so can cancer growth.

Any questions?

-: phenious :-