Thread: [FaD] New SARS Target Coming
May 23rd, 2003, 02:16 AM #1
[FaD] New SARS Target Coming
Just browsing the stats and noticed something new. A new query that hasn't started yet. It's 1P9T-Q3. Description from the site:
The coronavirus family exhibit one main proteinase sometimes described as '3C-like' because the nature of the catalytic site which fulfils a crucial role in the regulation of the virus life-cycle. The 3-D structure of the SARS virus proteinase has been determined by Professor Hilgenfeld at the University of Luebeck who has kindly made this structure available to Find-a-Drug. The catalytic or active site of this enzyme includes Cysteine and Histidine residues which are considered to be essential for the normal function of the protein. As part of the collaboration with Professor Hilgenfeld, the hits from this work will be made available to his group and they will attempt to confirm the binding to the protein site.
May 23rd, 2003, 05:51 AM #2mickwishGuest
Nifty. Thanks for the heads up, bitspit. I'll keep an eye out for that one.
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