Well, the bigger the screen, the higher resolution you will need to have a quality picture. If you look at a picture taken at 1 megapixel on a small 12" monitor, it will look good, look at it on a larger monitor and the quality would seem to diminish even though it is the same quality, the larger screen though will just make it easier to notice. So to answer, the question: yes. There will be a noticeable difference. On a screen that large though...I am not sure how big of a difference you will get from 7 megapixels to 10, but I would imagine it would be a big difference.