Personally, I like to have a slight negative pressure inside the case. It does make for more dust, but I think that by having a negative pressure, you will be pulling air in from all the cracks around your drives, thus keeping them cooler. Also, with a positive pressure, the air being pulled in from the front fans can recirculate the hot air inside the case. Whereas, if you have negative pressure, the air will go straight through the case and not have any time to recirculate. Just my oppinion, of course! Definitely have the air exhausting out the rear/top of the case though.