USB optical-cordless mouse = slower computer?

[Uncle Bob]

Just gotta throw in my $0.03. For a long time I used a Trackball
Explorer. I tried USB and PS/2. The only difference was occasionally the USB would get lost. I used the supplied software
to assign the button functions. I up graded to a cordless Trackman
Using supplied software to assign button function. I'm using the PS/2 now. USB works well also. Both of these mouse units worked
equally well USB or PS/2, but both units would occasionally get lost
when using USB.

[ArcticFox]

Nah, I still prefer USB.